MCL1 Antilichaam

Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

4170

Q07820

NP_068779.1

Human

MCL1 antibody was raised against a peptide sequence around aa.148~152 (N-N-T-S-T) derived from Human MCL1.

Unconjugated

Primary Antibodies

Apoptosis

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

42 kDa

This antibody detects endogenous level of total MCL1 protein.

Western Blot: 1:500~1:1000

MCL1

Myeloid cell leukemia sequence 1 (BCL2-related)

Homo sapiens

Bingle C. D., Craig R. W., Swales B. M., Singleton V., Zhou P., Whyle M. K. B. J. Biol. Chem. 275:22136-22146 (2000)

TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT, TUBB4, TM

WB

11386165

Liquid