MD-2/LY96, Human (His)

Myeloid differentiation factor-2 (MD2) (LY96 gene) is a small glycoprotein expressed by macrophages and dendritic cells. MD2 functions as a co-receptor for toll-like receptor (TLR) 4 and is required for its activation. Recognition of LPS by TLR4 requires MD-2 since most of the lipid chains of LPS interact with a hydrophobic pocket in MD-2. MD2 confers invasiveness by activating MAPK and NF-kB signaling pathways and inducing epithelial-mesenchymal transition[1][2]. MD-2/LY96 Protein, Human (His) is the recombinant human-derived MD-2/LY96 protein, expressed by E. coli , with C-10*His labeled tag.

MD-2/LY96 Protein, Human (His), Human, E. coli

12352202

95.00

23643 (Gene_ID) Q9Y6Y9-1/BAA78717 (E17-N160) (Accession)

Approximately 19 kDa, based on SDS-PAGE under reducing conditions.

Room temperature in continental US; may vary elsewhere.

Stored at -20°C for 2 years

Recombinant Proteins