MDC1 (fosfo Ser513) Antilichaam

The MDC1 protein contains a forkhead homology-associated (FHA) domain and 2 BRCA1 (MIM 113705) C-terminal motifs (BRCTs) and is required for the intra-S-phase DNA damage checkpoint.

9656

Q14676

NP_055456.2

Human

MDC1 (phospho Ser513) antibody was raised against a peptide sequence around phosphorylation site of Serine 513 (E-R-S (p) -Q-A) derived from Human MDC1.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

226 kDa

IgG

The antibody detects endogenous levels of MDC1 only when phosphorylated at serine 513.

MDC1

Mediator of DNA-damage checkpoint 1

Homo sapiens

Nagase T., DNA Res. 3:17-24 (1996) .

Shiina T., Genetics 173:1555-1570 (2006) .

Mungall A.J., Nature 425:805-811 (2003) .

IER3, NFBD1, KIAA0170, DKFZp781A0122

IHC

132626688

Liquid