MDFI-antilichaam - middengebied: FITC (ARP50514_P050-FITC)

MyoD family inhibitor

I-MF, I-mfa

4188

Q99750

NP_005577

Human, Cow, Dog, Pig, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the middle region of Human MDFI

This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.

PDIA5; USP20; ARID5A; ZNF266; KAT5; SPRY2; SPRY1; NR1H3; ZBTB24; ARHGAP32; KIAA0040; CREB5; MAGED1; ZNF264; GTF3C5; APLN; AKAP17A; ZNF230; ZNF223; ZNF155; ZNF138; ZNF136; ZNF124; ZNF79; WNT11; VHL; NR1H2; TYRO3; TNP2; TNNI1; TGIF1; GNAI2; GATA2; EIF4A2; D

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity purified

0.5 mg/ml

Cow: 79%; Dog: 79%; Human: 100%; Pig: 86%; Rabbit: 79%; Sheep: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

27kDa

Wet Ice

246

MDFI

MDFI

Rabbit

MyoD family inhibitor

AVTCQPQGNPLGCTPLLPNDSGHPSELGGTRRAGNGALGGPKAHRKLQTH