MDL-28170
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A potent and selective cell permeable calpain inhibitor. Inhibits oxidative damage-induced apoptosis in PC12 cells and capsaicin-induced apoptosis in dorsal root ganglion neurons.1 It penetrates the blood-brain barrier and inhibits brain cysteine protease activity after systemic administration, ameliorating brain damage in a gerbil model of global ischemia.2 Displays neuroprotective effects in neurotrama rodent models.3 Calpain I Ki = 8 nM; Cathepsin B Ki = 24 nM in isolated enzyme assays. IC50 = 0.3 µM in intact cell assay.4
Unconjugated
White solid
-20°C
Beschrijving
MDL-28170 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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