
ME 3407
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
ME-3407 (EF-4040) is a H+-K+-ATPase redistribution disruptor and myosin light chain kinase (MLCK) and protein kinase A inhibitor. ME-3407 blocks gastric acid secretion and aminopyrine accumulation by inhibiting microsomal-to-apical membrane redistribution of H+-K+-ATPase and suppressing MLCK-mediated myosin light chain phosphorylation. ME-3407 is promising for research of peptic ulcer[1].
133903-90-9
EF-4040
12352005
Myosin; Na+/K+ ATPase; PKA
Cytoskeleton; Membrane Transporter/Ion Channel; Stem Cell/Wnt; TGF-beta/Smad
Metabolism-protein/nucleotide metabolism
Metabolic Disease
O=C(OCCCC)CS(C1=NC2=CC=CN=C2S1)=O
C12H14N2O3S2
298.38
[1]Urushidani T, et al. ME-3407, a new antiulcer agent, inhibits acid secretion by interfering with redistribution of H (+) -K (+) -ATPase. Am J Physiol. 1997 May;272 (5 Pt 1) :G1122-34.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19133/
Reference compound1
No Development Reported
MLCK
Beschrijving
ME-3407 (EF-4040) is a H+-K+-ATPase redistribution disruptor and myosin light chain kinase (MLCK) and protein kinase A inhibitor. ME-3407 blocks gastric acid se
Specificaties
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