MED7 Antilichaam

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor- (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene.

9443

O43513

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human MED7 (NP_004261.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Growth Factors, Neuroscience, Signal Transduction

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 27kDa

IgG

WB: 1:500 - 1:2000

MED7

NIH/3T3

Mouse testis

Mediator complex subunit 7

Homo sapiens

CRSP9, ARC34, CRSP9, CRSP33

WB

Liquid