MEDI0639
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
MEDI0639 (21H3RK) is a human monoclonal antibody (mAb) targeting DLL4. MEDI0639 inhibits Notch1 binding to Dll4. MEDI0639 reverses Notch1-mediated growth inhibition of human umbilical vein endothelial cells in vitro. MEDI0639 promotes human angiogenesis and reduces the number of vessels covered by smooth muscle actin-positive mural cells. MEDI0639 can be used in Small cell lung cancer and solid tumors research[1].
21H3RK
12352203
Notch
Neuronal Signaling; Stem Cell/Wnt
Cancer-programmed cell death
Cancer
98.78
[MEDI0639]
[1]Jenkins DW, et al. MEDI0639: a novel therapeutic antibody targeting Dll4 modulates endothelial cell function and angiogenesis in vivo. Mol Cancer Ther. 2012 Aug;11 (8) :1650-60.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991423/MEDI0639-SDS-MedChemExpress.pdf
Inhibitory Antibodies
No Development Reported
Beschrijving
MEDI0639 (21H3RK) is a human monoclonal antibody (mAb) targeting DLL4. MEDI0639 inhibits Notch1 binding to Dll4. MEDI0639 reverses Notch1-mediated growth inhibi
Specificaties
Recent bekeken producten
Human Mast Cells - Dermis
ABC-TC105W
1 Vial
CYP1A2 Inhibitor Screening Assay
MA-0389
200 Well
Culture Medium for Immortalized Human Parathyroid Cells
AFG-ELL-2645-01
100 mL
Immortalized Human Parathyroid Cells
AFG-ELL-2055
> 1x 10^6 Cells / Vial
1,4- Dioxane Pure
1041330 500
500 mL
EPS8 Antibody (N-term) [APR32555G]
APR32555G-01
50 µL
Prestained Protein Ladder (25-300 kDa)
CRG1114
250 µL
Rat IgG Lyophilized
B2013903
25 mg
Recent gezochte producten
Hsa-miR-1258 mimic
HY-R00162-01
5 nmol
Hsa-miR-4258 mimic
HY-R00937-01
5 nmol
hsa-miR-1258 miRNA Mimic
MBS8298831-01
5 nmol
hsa-miR-4258 miRNA Mimic
MBS8299087-01
5 nmol
hsa-miR-1258 miRNA Agomir
MBS8311479-01
5 nmol
Hsa-miR-1258 miRNA Mimic
CMH0784-01
5 nmol
Hsa-miR-4258 miRNA Mimic
CMH1040-01
5 nmol
Hsa-miR-4258 miRNA Agomir
CMJ1040-01
5 nmol