
MEDI7814
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
MEDI7814 is a humanized monoclonal antibody inhibitor targeting C5a and C5adesArg. MEDI7814 binds to recombinant human C5a and serum purified human C5a with affinities of 14 pM and 8 pM, respectively. MEDI7814 is acute inflammatory diseases such as sepsis and renal ischemia-reperfusion injury[1].
12352100
Complement System
Immunology/Inflammation
Neuroscience-Neuromodulation
Cardiovascular Disease
[1]Colley CS, et al. Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors. MAbs. 2018 Jan;10 (1) :104-117.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991657/
Inhibitory Antibodies
No Development Reported
Beschrijving
MEDI7814 is a humanized monoclonal antibody inhibitor targeting C5a and C5adesArg. MEDI7814 binds to recombinant human C5a and serum purified human C5a with aff
Specificaties
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