MEDICA16 (Standaard)

Tacrine (hydrochloride) (Standard) is the analytical standard of Tacrine (hydrochloride) . This product is intended for research and analytical applications. Tacrine hydrochloride is a potent inhibitor of both AChE and BChE, with IC50s of 31 nM and 25.6 nM, respectively. Tacrine hydrochloride is also a NMDAR inhibitor, with an IC50 of 26 μM. Tacrine hydrochloride can be used for the research of Alzheimer’s disease[1][2].

87272-20-6

12352211

ATP Citrate Lyase; Free Fatty Acid Receptor; Reference Standards

GPCR/G Protein; Metabolic Enzyme/Protease; Others

Metabolic Disease

O=C(O)CC(C)(C)CCCCCCCCCCC(C)(C)CC(O)=O

C20H38O4

342.51

[1]Atkinson LL, et al. MEDICA 16 inhibits hepatic acetyl-CoA carboxylase and reduces plasma triacylglycerol levels in insulin-resistant JCR: LA-cp rats. Diabetes. 2002;51 (5) :1548-1555.|[2]Hara T, Hirasawa A, Sun Q, et al. Novel selective ligands for free fatty acid receptors GPR120 and GPR40. Naunyn Schmiedebergs Arch Pharmacol. 2009;380 (3) :247-255.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P1123R/

Reference Standards