Meglutol (standaard)

Meglutol (Standard) is the analytical standard of Meglutol. This product is intended for research and analytical applications. Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis) . Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases[1][2].

503-49-1

12352100

Autophagy; Endogenous Metabolite; HMG-CoA Reductase (HMGCR) ; Reference Standards

Autophagy; Metabolic Enzyme/Protease; Others

Metabolic Disease; Cardiovascular Disease

O=C(O)CC(C)(O)CC(O)=O

C6H10O5

162.14

[1]Leipnitz G, et al. Evidence that 3‐hydroxy‐3‐methylglutaric acid promotes lipid and protein oxidative damage and reduces the nonenzymatic antioxidant defenses in rat cerebral cortex[J]. Journal of neuroscience research, 2008, 86 (3) : 683-693.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B1189R/

Reference Standards