MEK5 (fosfo Ser311 / Thr315) Antilichaam

Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.

29568

Q62862

NP_001029159.1

Human, Mouse, Rat

MEK5 (phospho-Ser311/ Thr315) antibody was raised against a peptide sequence around phosphorylation site of Serine 311 and threonine 315 (V-N-S (p) I-A-K-T (p) -Y-V) derived from Rat MEK5.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

46 kDa

This antibody detects endogenous level of MEK5 only when phosphorylated at serine 311 or threonine 315.

Western Blot: 1:500~1:1000

Map2k5

Mitogen activated protein kinase kinase 5

Rattus

English J. M., Vanderbilt C. A., Xu S., Marcus S., Cobb M. H. J. Biol. Chem. 270:28897-28902 (1995)

Mek5, CDC2, CDC28A, CDKN1, P34CDC2, Map2k5

WB

77157802

Liquid