Melanoom geassocieerd antigeen D1 Antilichaam

Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.

94275

Q9QYH6

NP_062765.1

Mouse, Rat

Melanoma-associated antigen D1 antibodyPeptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1.

Unconjugated

Primary Antibodies

Apoptosis, Cancer

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

95 kDa

This antibody detects endogenous level of total Melanoma-associated antigen D1 protein.

Western Blot: 1:500~1:1000

Maged1

Melanoma antigen, family D, 1

Peptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1.

Zhao Z, et al. (2002) Sci China C Life Sci. 45 (4) : 412-20. Shen WG, et al. (2007) Cell Commun Adhes. 14 (1) : 21-31. Cheresh DA, et al. (1984) J Biol Chem. 259 (12) : 7453-9.

NRAGE, Dlixin, Dlxin1, Dlxin-1, MAGE-D1, mFLJ00163, DXBwg1492e, 2810433C11Rik, 5430405L04Rik, MAGED1

WB

9789935

Liquid