Melicopine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Melicopine is an alkaloid found in Z. simulans with antimalarial and anticancer activities. It exhibits inhibitory activity against chloroquine-sensitive 3D7 and chloroquine-resistant Dd2 strains of P. falciparum, with IC50 values of 29.7 and 33.7 µg/mL, respectively. Melicopine is cytotoxic to prostate cancer cells PC-3M and LNCaP (IC50 values of 47.9 and 37.8 µg/mL), but has no effect on non-cancerous HEK293 cells (IC50 greater than 100 µg/mL) . Melicopine holds promise for research in anticancer and anti-infection fields[1].
568-01-4
12352005
H302-H315-H319-H335
Insecticide; Parasite
Anti-infection; Others
Cancer; Infection
O=C1C2=C(N(C)C3=C4OCOC4=C(C(OC)=C13)OC)C=CC=C2
C17H15NO5
313.30
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
[1]Wang C, et al. Acridone alkaloids with cytotoxic and antimalarial activities from Zanthoxylum simullans Hance. Pharmacogn Mag. 2014 Jan;10 (37) :73-6.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W437569/
Natural Products
No Development Reported
Beschrijving
Melicopine is an alkaloid found in Z. simulans with antimalarial and anticancer activities. It exhibits inhibitory activity against chloroquine-sensitive 3D7 an
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