MEN-91507
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
MEN-91507 is an orally activecysteinyl leukotriene receptor 1 (CysLTR1) receptor antagonist. MEN-91507 behaves as insurmountable antagonist of Leukotriene D4 -induced calcium transients, with a pKb of 10.25. MEN-91507 can inhibit Leukotriene D4-induced bronchoconstriction and microvascular leakage in guinea-pigs. MEN-91507 can be used for the researches of inflammation, immunology[1].
197506-04-0
12352005
Leukotriene Receptor
GPCR/G Protein
Inflammation/Immunology
O=C1C=C(C2=NN=NN2)OC3=C(/C=C/C4=CC=C(OCCCCC5=CC=C(F)C=C5)C=C4)C=CC=C13
C28H23FN4O3
482.51
[1]Cabré F, et al. Pharmacological profile of MEN91507, a new CysLT (1) receptor antagonist. Eur J Pharmacol. 2002 Sep 20;451 (3) :317-26.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19395/
Reference compound1
No Development Reported
LTD4/CysLT1
Beschrijving
MEN-91507 is an orally activecysteinyl leukotriene receptor 1 (CysLTR1) receptor antagonist. MEN-91507 behaves as insurmountable antagonist of Leukotriene D4 -i
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