MESP2 Antilichaam - C-terminalgebied: FITC (ARP36921 T100-FITC)

Mesoderm posterior 2

BHLHc, bHLHc6

17293

O08574

NP_032615

Mouse, Rat

The immunogen is a synthetic peptide directed towards the C terminal region of mouse MESP2

Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng) . It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2.

Lfng

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

0.5 mg/ml

Mouse: 100%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

41kDa

Morimoto, M., et al., (2005) Nature 435 (7040), 354-359

Wet Ice

370

MESP2

MESP2

Rabbit

Mesoderm posterior protein 2

NM_008589

SCQRLQPQPQPQPQWGCWGHDAEVLSTSEDQGSSPALQLPVASPTPSSGL