MET G1163R Recombinant humaan actief eiwit Kinase
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Mesenchymal-to-epithelial transition (MET) is a receptor tyrosine kinase for hepatocyte growth factor (HGF) . MET overactivation is strongly associated with angiogenesis, cellular motility, growth, and invasion. Aberrant MET signaling can drive tumorigenesis in several cancer types through various molecular mechanisms, including MET amplification, MET exon 14 skipping mutation, MET overexpression, and MET fusions. MET G1163R is a mutant of MET. MET G1163R Recombinant Human Active Protein Kinase is a recombinant MET G1163R protein that can be used to study MET G1163R-related functions[1].
12352211
C-Met/HGFR
Protein Tyrosine Kinase/RTK
Cancer-Kinase/protease
Cancer
[METG1163RRecombinantHumanActiveProteinKinase]
[1]Kang J, et al. Response and acquired resistance to MET inhibitors in de novo MET fusion-positive advanced non-small cell lung cancer. Lung Cancer. 2023 Apr;178:66-74.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-E70751/
Enzyme
No Development Reported
Beschrijving
Mesenchymal-to-epithelial transition (MET) is a receptor tyrosine kinase for hepatocyte growth factor (HGF) . MET overactivation is strongly associated with ang
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