Methantheline (bromide)

Methantheline bromide is a quaternary Ammonium derivate with anticholinergic activity. Methantheline bromide results in a significant greater reduction of axillary sweat production. Methyl bromide can be used in the research of intractable peptic ulcers[1][2].

53-46-3

12352005

H302-H332

Drug Derivative; mAChR

GPCR/G Protein; Neuronal Signaling; Others

Metabolic Disease; Inflammation/Immunology

O=C(OCC[N+](CC)(CC)C)C1C2=C(OC3=C1C=CC=C3)C=CC=C2.[Br-]

C21H26BrNO3

420.34

P261-P264-P270-P271-P304+P340-P330-P501

[1]LIEBOWITZ D, et al. Treatment of intractable peptic ulcer with methantheline (banthine) bromide. J Am Med Assoc. 1952 Oct 18;150 (7) :672-8. English, Undetermined Language. |[2]Müller C, et al. Efficacy and safety of methantheline bromide (Vagantin (®) ) in axillary and palmar hyperhidrosis: results from a multicenter, randomized, placebo-controlled trial. J Eur Acad Dermatol Venereol. 2013 Oct;27 (10) :1278-84.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B1689A/

Reference compound1

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