Methionine Aminopeptidase 2 (METAP2) Mouse Monoclonal Antibody [Kloon ID: LBI1F6]

This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) METAP2 mouse monoclonal antibody, clone LBI1F6

MAP2; MNPEP; p67eIF2

Homo sapiens methionyl aminopeptidase 2 (METAP2), transcript variant 1, mRNA.

10988

P50579

Unconjugated

WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Protease

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

METAP2

https://www.ncbi.nlm.nih.gov/gene/?term=10988

https://www.uniprot.org/uniprot/P50579