Methosulide
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Methosulide (Compound 1d) is a selective COX-2 inhibitor with an IC50 value of 2.31 μM. Methosulide can be used in the research of inflammatory diseases[1].
51765-76-5
12352005
H317
COX
Immunology/Inflammation
Inflammation/Immunology
COC1=CC=C(C=C1)OC2=C(C=CC(=C2)[N+](=O)[O-])NS(=O)(=O)C
C14H14N2O6S
338.34
P261-P272-P280-P302+P352-P362+P364-P501
[1]Yamamoto Y, et al. Isomeric methoxy analogs of nimesulide for development of brain cyclooxygense-2 (COX-2) -targeted imaging agents: Synthesis, in vitro COX-2-inhibitory potency, and cellular transport properties. Bioorg Med Chem. 2015 Nov 1;23 (21) :6807-14.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W792524/
Reference compound1
No Development Reported
COX-1; COX-2
Beschrijving
Methosulide (Compound 1d) is a selective COX-2 inhibitor with an IC50 value of 2.31 μM. Methosulide can be used in the research of inflammatory diseases[1].
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