MettL7B Antilichaam

MettL7B Antibody: MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

196410

Q6UX53

NP_689850

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

MettL7B Antibody is affinity chromatography purified via peptide column.

Cat. No. 1466 - Rat Spleen Tissue Lysate

1 mg/mL

MettL7B Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

MettL7B antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

This MettL7B antibody is predicted to not cross-react with MettL7A.

METTL7B

Cat. No. 10-901 - Human Spleen Tissue Slide

Methyltransferase like 7B

Homo sapiens

Clark HF, Gurney AL, Abaya E, et al. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. Genome Res.2003; 13:2265-70.

Li E, Bestor TH, and Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell1992; 69:915-26.

Laird PW and Jaenisch R. DNA Methylation and Cancer. Human Molecular Genetics1994; 3:1487-95.

MettL7B Antibody: ALDI, Methyltransferase-like protein 7B

ELISA, WB, IHC-P

164663805

Liquid