MG-101 (GMP)

MG-101 (GMP) (Calpain inhibitor I (GMP) ) is MG-101 produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer[1].

110044-82-1

Calpain inhibitor I (GMP) ; Ac-LLnL-CHO (GMP) ; ALLN (GMP)

12352211

Apoptosis; Proteasome

Apoptosis; Metabolic Enzyme/Protease

Cancer

O=C(N[C@H](C=O)CCCC)[C@@H](NC([C@@H](NC(C)=O)CC(C)C)=O)CC(C)C

C20H37N3O4

383.53

[1]Li SZ, et al. ALLN hinders HCT116 tumor growth through Bax-dependent apoptosis. Biochem Biophys Res Commun. 2013 Jul 26;437 (2) :325-330.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-18964G/

GMP Small Molecules

No Development Reported