MG-1131
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
MG-1131 is a human monoclonal antibody (mAb) targeting TIGIT. MG-1131 activates NF-κB signaling in T cells and enhances NK-mediated tumor killing activity in a PVR-dependent manner. MG-1131 blocks TIGIT to increase IFN-γ secretion. MG-1131 can be used in anti-tumor immunity research. Recommended isotype control: Human IgG1 kappa, Isotype Control.
12352203
IFNAR; NF-κB; Transmembrane Glycoprotein
Immunology/Inflammation; NF-κB
Cancer-programmed cell death
Cancer
[MG-1131]
[1]Lee J, et al. Unveiling the Impact of BMP9 in Liver Diseases: Insights into Pathogenesis and Therapeutic Potential. Biomolecules. 2024 Aug 15;14 (8) :1013.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991475/
Inhibitory Antibodies
No Development Reported
Beschrijving
MG-1131 is a human monoclonal antibody (mAb) targeting TIGIT. MG-1131 activates NF-κB signaling in T cells and enhances NK-mediated tumor killing activity in a
Specificaties
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