MGA Antilichaam - C-terminaal gebied: Biotine (ARP47556_P050-Biotine)

MAX gene associated

MAD5, MXD5

23269

Q8IWI9-2

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the C-terminal region of Human MGA

MGA functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes and functions as a repressor or an activator. It binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. It suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. It function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor

SUMO2; SUMO3; EED; RNF2; MAX; SMAD1; LSM8; UBC; CD2BP2; CBX2; PCGF6; RYBP; PCGF3; YAF2; CBX4; CBX3; E2F4; E2F3; E2F1

Biotin

Polyclonal Antibody

WB

Affinity Purified

MGA is supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Cow: 92%; Dog: 85%; Horse: 92%; Human: 100%; Mouse: 79%; Pig: 92%; Rabbit: 79%; Rat: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

76kDa

Wet Ice

697

MGA

MGA

Rabbit

MAX gene-associated protein

ASLQMKRESQNPDQKDETNSIKREQETKKVLQSEGEAVDPEANVIKQNSG