MGAT1 (NM 002406) Humaan Recombinant Proteïne

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Purified recombinant protein of Human mannosyl (alpha-1, 3-) -glycoprotein beta-1, 2-N-acetylglucosaminyltransferase (MGAT1), transcript variant 2, Trp241-end, with N-terminal His tag, expressed in E. coli, 50ug

GLCNAC-TI; GLCT1; GLYT1; GNT-1; GNT-I; GnTI; MGAT

4245

P26572

NM_002406

5q35.3

E. coli

N-His

Metabolic pathways, N-Glycan biosynthesis

Metabolic pathways, N-Glycan biosynthesis

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

50mM Tris, 8M Urea, pH8.0

Druggable Genome, Transmembrane

24.2 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

MGAT1

Human

NP_002397

https://www.ncbi.nlm.nih.gov/gene/4245

https://www.uniprot.org/uniprot/P26572

https://www.ncbi.nlm.nih.gov/nuccore/NM_002406

https://www.ncbi.nlm.nih.gov/nuccore/NP_002397