MGD010
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
MGD010 is a bispecific CD32B (FcγRIIb) and CD79B antibody. MGD010 inhibits activated B-cells by delivering a negative signal via simultaneous co-ligation of CD32B (FcγRIIb), with the BCR component, CD79B. MGD010 has the potential for the study of autoimmune disorders[1].
PRV-3279
12352203
Fc Receptor (FcR)
Immunology/Inflammation
COVID-19-immunoregulation
Inflammation/Immunology
[1]Pandya, N., et al. OP0201 Safety, Tolerability, and Functional Activity of MGD010, A Dart® Molecule Targeting CD32B and CD79B, Following A Single Dose Administration in Healthy Volunteers. Annals of the Rheumatic Diseases, 2016. 75 (Suppl 2), 132.3-133.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991086/
Inhibitory Antibodies
Phase 2
Beschrijving
MGD010 is a bispecific CD32B (FcγRIIb) and CD79B antibody. MGD010 inhibits activated B-cells by delivering a negative signal via simultaneous co-ligation of CD3
Specificaties
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