Midkine Recombinant Proteïne

Midkine and its functionally-related protein Pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK) . MK plays an important regulatory role in epithelial-mesenchymal interactions during fetal development and in postnatal lung development. MK chemoattracts embryonic neurons, neutrophils and macrophages, and by signaling through the ALK receptor it exerts angiogenic, growth and survival activities during tumorgenesis. Recombinant murine Midkine is a 13.4 kDa protein containing 121 amino acid residues including five intra-molecular disulfide bonds.

17242

P12025

NP_001012335.1

Recombinant Proteins

E. coli

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Room Temp

The lyophilized Midkine recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted Midkine stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing Midkine recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Midkine

Mus musculus

MK, Mek, Mk, Midkine, Retinoic acid-induced differentiation factor, MK

Murine

59894790

Lyophilized