MIER1 Antilichaam - middengebied: Biotine (ARP34468_T100-Biotine)

Mesoderm induction early response 1 homolog (Xenopus laevis)

ER1, MI-ER1

57708

Q8NES5

NP_065999

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human MIER1

The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1) .

TMEM171; SOX2; HDAC2; HDAC1; EHMT2; CDYL; TUBB1; APP; ELAVL1; UBC; CREBBP; SP1

Biotin

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

49kDa

Paterno, G.D., et al., (1998) Gene 222 (1), 77-82

Wet Ice

536

MIER1

MIER1

Rabbit

Mesoderm induction early response protein 1

NM_020948

RRTGDEKGVEAIPEGSHIKDNEQALYELVKCNFDTEEALRRLRF