Migalastat
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Migalastat is a potent, selective, and orally available inhibitor of α-galactosidase A (IC50= 40 nM) .1 It binds to mutant misfolded α-GalA shifting the folding behavior toward functional active conformation (pharmacological chaperone activity) followed by trafficking to the lysosomes.2 Migalastat is active broadly across species from Drosophila3 to human4. Clinically useful agent for Fabry disease.5
Unconjugated
White solid
-20°C
Beschrijving
Migalastat Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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