Migalastat (hydrochloride) -15N

Migalastat hydrochloride-15N (GR181413A-15N) is the 15N-labeled Migalastat hydrochloride. Migalastat (GR181413A free base) hydrochloride is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity[1].

1219134-37-8

GR181413A-15N

12352005

Glycosidase; Isotope-Labeled Compounds

Metabolic Enzyme/Protease; Others

Others

O[C@H]1[C@H]([C@H]([15NH]C[C@@H]1O)CO)O.Cl

C6H14Cl 15NO4

200.63

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W740650/

Isotope-Labeled Compounds

No Development Reported