MIP-1 gamma (CCCL9/10)

MIP-1γ is a CC chemokine found in murine blood and a wide variety of murine tissues, with no known human homolog. MIP-1γ signals through the CCR1 receptor. MIP-1γ chemoattracts neutrophils and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1γ contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant murine MIP-1γ is an 11.6 kDa protein containing 101 amino acid residues.

Ccl9; CCF18; MRP-2; Scya9; Scya10

20308

P51670

NP_035468.1

NM_011338.2

11 C; 11 47.4 cM

Mouse

Human

QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q

< 0.1 ng/µg of protein (< 1EU/µg)

> 98% by SDS-PAGE & HPLC analyses

Determined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10.0 ng/ml.

101

Lyophilized

11.6 kDa

E. coli