MIP-2 (CXCL2, Gro-beta)

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant mouse MIP-2 is a 7.8 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

Cxcl2; GROb; Gro2; Mip2; Scyb; MIP-2; Scyb2; MIP-2a; Mgsa-b; CINC-2a

20310

P10889

NP_033166.1

NM_009140.2

5 E1; 5 51.0 cM

Mouse

Human, Mouse

AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KAN

< 0.1 ng/µg of protein (< 1EU/µg)

> 98% by SDS-PAGE & HPLC analyses

Determined by its ability to chemoattract total human neutrophils using a concentration range of 1.0-10.0 ng/ml.

73

Lyophilized

7.8 kDa

E. coli