MIP-3 alfa (CCL20)

MIP-3 alpha is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3 alpha is an 8.0 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

CKb4; LARC; ST38; MIP3A; MIP-3a; SCYA20; MIP-3-alpha

6363

P78556

NP_004582.1

NM_004591

9p13

Human

Mouse, Rat, Human

ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM

< 0.1 ng/µg of protein (< 1EU/µg)

> 98% by SDS-PAGE & HPLC analyses

Determined by its ability to chemoattract human T cells using a concentration of 10.0-50.0 ng/ml.

70

Lyophilized

8.0 kDa

E. coli