MIP-3 bèta (CCL19)

MIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Mouse urine MIP-3β is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Ccl19; ELC; CKb11; MIP3B; Scya19; exodus-3

24047

O70460

NP_036018.1

NM_011888

4 A5; 4

Mouse

Human, Mouse, Monkey, Leech, Rat

GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS

< 0.1 ng/µg of protein (< 1EU/µg)

> 98% by SDS-PAGE & HPLC analyses

Determined by its ability to chemoattract human mature dendritic cells using a concentration range of 10.0-100.0 ng/ml.

83

Lyophilized

9.2 kDa

E. coli