Mitofusine 2 Antilichaam

This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

170731

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 687-757 of mouse Mitofusin 2 (NP_573464.2) .

Unconjugated

Primary Antibodies

Apoptosis, Autophagy, Cancer, Cell Cycle, Neuroscience, Signal Transduction

Affinity purification

Mouse brain

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 86kDa

IgG

MFN2

Rat brain

Mitofusin 2

Mus musculus

D630023P19Rik, Fzo, mitofusin-2, HSG protein, hypertension related protein 1, mitochondrial assembly regulatory factor, transmembrane GTPase MFN2

WB, IHC

Liquid