MK-4166
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
MK-4166 is a humanized IgG1 agonist monoclonal antibody targeting GITR. MK-4166 enhances the proliferation of both naïve and tumor-infiltrating T lymphocytes[1].
12352203
TNF Receptor
Apoptosis
Cancer-programmed cell death
Cancer
98.20
[MK-4166]
(145.2 kDa)
[1]Sukumar S, et al. Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells. Cancer Res. 2017;77 (16) :4378-4388.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991179/MK-4166-SDS-MedChemExpress.pdf
Inhibitory Antibodies
Phase 1
Beschrijving
MK-4166 is a humanized IgG1 agonist monoclonal antibody targeting GITR. MK-4166 enhances the proliferation of both naïve and tumor-infiltrating T lymphocytes[1]
Specificaties
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