MK-4830
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
MK-4830 is a fully humanized monoclonal antibody of the immunoglobulin G4 subclass that specifically binds to ILT4 and blocks its interaction with HLA-G and other ligands. MK-4830 inhibits tumor growth in humanized mouse cancer models[1].
12352203
Others
Others
Cancer-programmed cell death
Cancer
[MK-4830]
[1]Lillian L Siu, et al. First-in-Class Anti-immunoglobulin-like Transcript 4 Myeloid-Specific Antibody MK-4830 Abrogates a PD-1 Resistance Mechanism in Patients with Advanced Solid Tumors. Clin Cancer Res. 2022 Jan 1;28 (1) :57-70.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991230/
Inhibitory Antibodies
Phase 2
Beschrijving
MK-4830 is a fully humanized monoclonal antibody of the immunoglobulin G4 subclass that specifically binds to ILT4 and blocks its interaction with HLA-G and oth
Specificaties
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