ML210
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
ML210 is selectively synthetic lethal to HRAS expressing cells compared to isogenic non-HRAS cells (IC50 = 7.1 nM for BJeLR (expressing HRASg12v) cells vs IC50 = 272 nM for BJeH-LT (non-HRAS expressing) cells.1 ML210 is able to inhibit glutathione peroxidase 4 (GPX4), an important selenoenzyme that protects cells from ferroptosis caused by iron catalyzed formation of free radicals from lipid peroxides.2,3 Treatment of several treatment-resistant cancer cell lines exhibiting a high mesenchymal state with ML210 resulted in selective induction of ferroptosis.3
Unconjugated
White solid
RT
Beschrijving
ML210 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
Cellubrevin Antibody
MBS9436639-01
0.05 mL
Oxidative Stress Combo Assay Tissue Kit
EA-7008
1 Each
Arachis hypogaea Lectin (PNA) - Biotinylated
21510020-1
5mg
1,4- Dioxane Pure
1041330 500
500 mL
Benzonase ELISA Kit
EG23601S
96 Tests
Not I Restriction Enzyme
B2016623
500 Units
K562-HLA-G0101 Overexpressing Cell Line
RG-1214
5x 10^6
Yeast Poly (A) Polymerase
RNT-006-S
30000 Units
Recent gezochte producten
Cellubrevin Antibody
MBS9436639-01
0.05 mL
Rat Oxidative Stress Primer Library
ROSL-I
1 set
DTNB (Ellman’s) Thiol Oxidative Stress Assay
1021
1 Kit
OSR1 (Oxidative Stress Responsive 1)
MBS616581-01
0.1 mL
Oxidative Stress Combo Assay Cell Kit
EA-7006
1 Each
Oxidative Stress Combo Assay Blood Kit
EA-7007
1 Each
Oxidative Stress Combo Assay Tissue Kit
EA-7008
1 Each
OSR1 (Oxidative Stress Responsive 1)
O8054
100 µL