ML277
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
ML277 is a potent (EC50 = 260 nM) activator of Kv7.1 with selectivity against Kv7.2, Kv7.4, and Kv11.1 (hERG) .1 ML277 enhances cardiac delayed rectifier K+ currents (IKs) in human iPSC-derived cardiomyocytes from normal and long QT-interval syndrome afflicted patients suggesting potential therapeutic use in long QT-interval syndrome.2,3 It displayed cardioprotective effects against ischemia in cellular and whole-heart models.4
Unconjugated
White solid
-20°C
Beschrijving
ML277 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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