MLC1 Antilichaam - middengebied: Biotine (ARP35249_P050-Biotine)

Megalencephalic leukoencephalopathy with subcortical cysts 1

VL, LVM, MLC

23209

Q15049

NP_055981

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human MLC1

MLC1 may be a transporter. It may act as a non-selective neuronal cation channel.The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.

KDM1A; PRMT6; Cav2; Dtnb; Snta1; Dtna; Tuba1a; Kcnj10; Cav1; UBC; TPT1; DAPK2; MYLK

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 91%; Dog: 86%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 93%; Rabbit: 83%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

41kDa

Ambrosini, E., (2008) Mol. Cell. Neurosci. 37 (3), 480-493

Wet Ice

377

MLC1

MLC1

Rabbit

Membrane protein MLC1

NM_015166

SDSANILDEVPFPARVLKSYSVVEVIAGISAVLGGIIALNVDDSVSGPHL