MLH1 Mouse Monoclonal Antibody [Kloon ID: UMLBI191]

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. [provided by RefSeq, Nov 2009]

Carrier-free (BSA/glycerol-free) MLH1 mouse monoclonal antibody, clone UMLBI191

COCA2; FCC2; hMLH1; HNPCC; HNPCC2; MMRCS1

Homo sapiens mutL homolog 1 (MLH1), transcript variant 1, mRNA.

4292

P40692

Unconjugated

Colorectal cancer, Endometrial cancer, Mismatch repair, Pathways in cancer

Colorectal cancer, Endometrial cancer, Mismatch repair, Pathways in cancer

IHC 1:200

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

MLH1

https://www.ncbi.nlm.nih.gov/gene/?term=4292

https://www.uniprot.org/uniprot/P40692