MLL4 Antilichaam - N-terminal regio : HRP (ARP33704_T100-HRP)

Myeloid/lymphoid or mixed-lineage leukemia 4

HRX2, MLL2, MLL4, TRX2, WBP7, DYT28, MLL1B, WBP-7, CXXC10

9757

Q9UMN6-2

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

The immunogen is a synthetic peptide directed towards the N terminal region of human MLL4

MLL4 a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. MLL4 is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer

UBC; SMAD3; ZNF512B; ATXN1; HIST2H3C; WDR5; ASH2L; RBBP5; SEPT8; RPP14; NREP; TSC22D1; TK1; SMN1; RAP1B; PIN1; GRB7; RCC1; CDKN1A; ATP1B1; ANXA7; ANXA1; BCL6; WDR82; PAGR1; PAXIP1; NCOA6; SMARCB1; PRPF40A

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

KMT2B is strongly supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 92%; Dog: 85%; Guinea Pig: 92%; Horse: 83%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%; Yeast: 91%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

64kDa

FitzGerald, K.T., et al., (1999) Genomics 59 (2), 187-192

Wet Ice

582

KMT2B

KMT2B

Rabbit

Histone-lysine N-methyltransferase MLL4

WAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDEEEFQGFHSDEDVA