MMP11 Mouse Monoclonal Antibody [Kloon ID: LBI3E10]

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) MMP11 mouse monoclonal antibody, clone LBI3E10

SL-3; ST3; STMY3

Homo sapiens matrix metallopeptidase 11 (MMP11), transcript variant 1, mRNA.

4320

P24347

Unconjugated

WB 1:500

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Protease

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

MMP11

https://www.ncbi.nlm.nih.gov/gene/?term=4320

https://www.uniprot.org/uniprot/P24347