MMP13 Mouse Monoclonal Antibody [Kloon ID: LBI2D11]

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) MMP13 mouse monoclonal antibody, clone LBI2D11

CLG3; MANDP1; MDST; MMP-13

Homo sapiens matrix metallopeptidase 13 (MMP13), mRNA.

4322

P45452

Unconjugated

WB 1:4000, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Protease

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

MMP13

https://www.ncbi.nlm.nih.gov/gene/?term=4322

https://www.uniprot.org/uniprot/P45452