MMP7 (NM 002423) Humaan Recombinant Proteïne

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs) . Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]

Purified recombinant protein of Human matrix metallopeptidase 7 (matrilysin, uterine) (MMP7), Tyr95-End, with N-terminal His tag, expressed in E. coli, 50ug

MMP-7; MPSL1; PUMP-1

4316

P09237

NM_002423

11q22.2

E. coli

N-His

Wnt signaling pathway

Wnt signaling pathway

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

50mM Tris, 8M Urea, pH8.0.

Druggable Genome, Protease

19.1 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

MMP7

Human

NP_002414

https://www.ncbi.nlm.nih.gov/gene/4316

https://www.uniprot.org/uniprot/P09237

https://www.ncbi.nlm.nih.gov/nuccore/NM_002423

https://www.ncbi.nlm.nih.gov/nuccore/NP_002414