MMS19 Polyklonale Antilichaam, HRP Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
MET18; MMS19L; hMMS19; MMS19 nucleotide excision repair protein homolog; MET18 homolog; MMS19-like protein; MMS19
64210
Q96T76
Nucleus
• Rabbit
Human, Mouse
851-950/1030
MMS19
• Polyclonal
• IgG
HRP
KLH conjugated synthetic peptide derived from human MMS 19
WB, ELISA, IHC-P, IHC-F
Purified by Protein A.
1µg/µl
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
64210
Rat, Dog, Pig, Horse, Rabbit
Beschrijving
MMS19 Polyklonale Antilichaam, HRP Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
Specificaties
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