MO-2097
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2744300-63-6
ROS, Apoptosis, Caspase, MEK, ERK, HIF/HIF Prolyl-Hydroxylase, Raf
Immunology/Inflammation, Metabolism, Apoptosis, Proteases/Proteasome, Chromatin/Epigenetic, MAPK
MO-2097 is an inhibitor of RAF-1 and HIF-1α. It destabilizes RAF-1, reducing EMT-related transcription factors and mesenchymal markers. MO-2097 suppresses HIF-1α protein expression under hypoxic or hypoxia-mimicking conditions via hnRNPA2B1. It induces mitochondrial ROS production, leading to cell apoptosis. By inhibiting the RAF/MEK/ERK signaling pathway, MO-2097 effectively prevents colorectal cancer metastasis. It also inhibits tumor growth in human colorectal cancer HCT116 cell xenograft mouse models. MO-2097 is applicable for colorectal cancer research.
OC=1C=C(O)C=C(C1)C=2OC=3C=C4OCC(=CCC4=CC3C2)C
C19H16O4
308.33
Ice Packs
-20°C
Beschrijving
MO-2097 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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