Mopidralazine (hydrochloride)

Mopidralazine hydrochloride (MDL-899) (Compound 30) is an orally active antihypertensive agent. Mopidralazine hydrochloride significantly reduces systolic blood pressure (ED50 = 1.94 mg/kg) in spontaneously hypertensive rats models. Mopidralazine hydrochloride has a slower onset of action but a longer duration of action and has a significantly smaller effect on increasing heart rate in canine model of renal hypertension. Mopidralazine hydrochloride can be used for the research of hypertension[1].

86703-02-8

MDL-899

12352005

Others

Others

Cardiovascular Disease

CC1=CC=C(C)N1NC2=NN=C(N3CCOCC3)C=C2.Cl

C14H20ClN5O

309.79

[1]Bellasio E, et al. Antihypertensives. N-1H-Pyrrol-1-yl-3-pyridazinamines. J Med Chem. 1984 Aug;27 (8) :1077-83.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-180354/

Reference compound1

No Development Reported