MRP5 Polyklonale Antilichaam, PE-Cy5 Vervoeging

MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs) . MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone) . MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.

Multidrug Resistanec-Associated Protein 5; ABC 33; ABC33; ABCC 5; ABCC5; ATP binding cassette sub family C CFTR/MRP member 5; ATP binding cassette sub family C member 5; Canalicular multispecic organic anion transporter C; DKFZp686C1782; EST277145; MOAT C; MOATC; MRP 5; Multi specic organic anion tranporter C; pABC 11; pABC11; SMRP; MRP5_HUMAN.

10057

Cell membrane

Rat

61-180/1436

MRP5

PE-Cy5

KLH conjugated synthetic peptide derived from human MRP5

WB

Purified by Protein A.

488nm/670nm

1µg/µl

WB (1:300-5000)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

10057

Human, Mouse