MRPS18B Antilichaam

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.

28973

Q9Y676

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-258 of human MRPS18B (NP_054765.1) .

Unconjugated

Primary Antibodies

Other

Affinity purification

U-87MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 35kDa

IgG

MRPS18B

A-431

Mouse kidney

Mouse brain

Rat heart

Rat kidney

Mitochondrial ribosomal protein S18B

Homo sapiens

C6orf14, HSPC183, HumanS18a, MRP-S18-2, MRPS18-2, PTD017, S18amt, 28S ribosomal protein S18b, mitochondrial, 28S ribosomal protein S18-2, mitochondrial, MRP-S18-b, S18mt-b, mitochondrial ribosomal protein S18-2, mitochondrial small ribosomal subunit protein bS18b, mitochondrial small ribosomal subunit protein bS18m-B, mitochondrial small ribosomal subunit protein mS4mrps18-b

WB, IHC

Liquid